Tuesday, July 15, 2025

Allopathic Medicine and Traditional & other Complementary Medicine


by: lim ju boo


Professor Dr Marilyn Li Ching who is a regular contributor in a WhatsApp group recently sent me this video for my comment. 

1. How Medicine was Hijacked 

https://www.youtube.com/watch?v=0KN9A8tbULU

Professor Dr Ling Siew Ching also separately sent me another video last month for my attention 

2. Dr Peter Gotzsche on drugs as 3rd leading cause of death


https://www.youtube.com/watch?v=dozpAshvtsA


There is also another video I saw here: 

3. Deadly Medicines and Organised Crime: How Big Pharma Has Corrupted Healthcare

https://www.goodreads.com/book/show/18428805-deadly-medicines-and-or-


After viewing all these videos. here's my comment. 


But first, let me write very briefly on the history of medicine.  

History of medicine: 

The transition from natural remedies to synthetic drugs was driven by scientific advancements but also by corporate profit motives. While synthetic drugs have saved lives, the modern pharmaceutical industry prioritizes patents, high pricing, and market control over accessibility and affordability. The challenge remains in balancing innovation with ethical medicine.

As far as I know the earliest records of natural products were depicted on clay tablets in cuneiform from Mesopotamia (2600 B.C.) which documented oils from Cupressus sempervirens (Cypress) and Commiphora species (myrrh) which are still used today to treat coughs, colds and inflammation . The Ebers Papyrus (2900 B.C.) is an Egyptian pharmaceutical record, which documents over 700 plant-based drugs ranging from gargles, pills, infusions, to ointments. The Chinese Materia Medica (1100 B.C.) (Wu Shi Er Bing Fang, contains 52 prescriptions), Shennong Herbal (~100 B.C., 365 drugs) and the Tang Herbal (659 A.D., 850 drugs) are documented records of the uses of natural products . The Greek physician, Dioscorides, (100 A.D.), recorded the collection, storage and the uses of medicinal herbs, whilst the Greek philosopher and natural scientist, Theophrastus (~300 B.C.) dealt with medicinal herbs. 

Aspirin's discovery began with the ancient use of willow bark for pain relief, leading to the synthesis of acetylsalicylic acid (aspirin) by Felix Hoffmann at Bayer in 1897, which was then marketed as a pain reliever in 1899. The use of willow bark for pain relief and fever reduction dates back thousands of years, with Sumerians and Egyptians using it for medicinal purposes. The synthesis of Aspirin started in 1897, when Felix Hoffmann, a chemist at the Bayer company, synthesized acetylsalicylic acid (ASA), the active ingredient in aspirin, by modifying salicylic acid. Bayer, was a German pharmaceutical company that patented the process and marketed the drug under the name "Aspirin" in 1899. After Aspirin lost its patent rights, other pharmaceutical companies began to manufacture other analgesics such as NSAID (non-steroidal anti-inflammatory drugs). 

The same scenario is with other antibiotics after the discovery of penicillin after the Scottish bacteriologist Alexander Fleming accidentally discovered penicillin in 1928 while working at St. Mary's Hospital in London, noticing a mold inhibiting bacterial growth on a contaminated petri dish, leading to the development of the first 

First of all, I must straight away say it is not entirely true that drugs are unless. There are many drugs that are life-saving and irreplaceable as they can act very fast to stabilize a patient especially in a medical emergency. I have written some examples here:


 

 Here are further examples:

1. Epinephrine (Adrenaline) – Used in anaphylaxis (severe allergic reactions) and cardiac arrest.
2. Aspirin – Essential for heart attack and stroke prevention.
3. Insulin – Vital for type 1 diabetes management.
4. Antibiotics (Penicillin, Vancomycin, Meropenem, etc.) – Critical for bacterial infections and sepsis.
5. Steroids (Dexamethasone, Prednisone) – Used for severe inflammatory conditions and autoimmune disorders.
6. Anticoagulants (Heparin, Warfarin, DOACs) – Prevent blood clots that could cause strokes or pulmonary embolisms.
7. Antiviral Drugs (Tamiflu, Paxlovid, Remdesivir, etc.) – Used for severe viral infections, including influenza, COVID-19, and HIV/AIDS.
8. Chemotherapy Drugs (Cisplatin, Doxorubicin, Imatinib, etc.) – Essential for treating various cancers.
9. IV Fluids and Electrolytes – Lifesaving in dehydration, shock, and metabolic imbalances.
10. Oxygen Therapy & Ventilators – Indispensable in respiratory failure, pneumonia, and critical care settings.

Some of these drugs especially emergency drugs, and powerful antibiotics are very life savings. 

While many chronic diseases require lifestyle-based solutions, there are pharmaceutical drugs that have undoubtedly saved millions of lives. 

As I have some training in emergency medicine let me very briefly in a nutshell explore this area.  

Here are more key examples of life-saving drugs that are absolutely essential. 

A. Emergency & Critical Care Drugs

  1. Epinephrine (Adrenaline) – Used for anaphylactic shock, severe asthma attacks, and cardiac arrest.
  2. Atropine – Used in emergencies to increase heart rate during severe bradycardia (slow heartbeat).
  3. Norepinephrine & Dopamine – Critical for septic shock to maintain blood pressure and circulation.
  4. Aspirin (Acetylsalicylic Acid) – Rapidly given during heart attacks to prevent clot expansion.
  5. Nitroglycerin – Used to relieve angina (chest pain) and heart attacks by dilating coronary arteries.
  6. Thrombolytics (e.g., Alteplase, Streptokinase, Tenecteplase) – Dissolve blood clots in strokes and heart attacks.

B. Life-Saving Antibiotics & Antivirals

  1. Penicillin & Cephalosporins – Still crucial for treating bacterial infections like pneumonia, syphilis, and meningitis.
  2. Vancomycin – One of the last-resort antibiotics for MRSA (Methicillin-resistant Staphylococcus aureus) infections.
  3. Doxycycline & Azithromycin – Effective against malaria, bacterial pneumonia, and Lyme disease.
  4. Rifampin & Isoniazid – Key drugs for tuberculosis treatment.
  5. Oseltamivir (Tamiflu) & Remdesivir – Used for severe cases of influenza and COVID-19.
  6. HIV Antiretroviral Therapy (ART) – Drugs like Tenofovir, Efavirenz, and Dolutegravir allow HIV-positive individuals to live long lives with undetectable viral loads.

C. Surgical & Anesthetic Drugs

  1. Propofol & Midazolam – Used in surgeries and intensive care for anesthesia and sedation.
  2. Lidocaine & Bupivacaine – Local anesthetics for pain relief during procedures.
  3. Heparin & Warfarin – Essential for preventing deadly blood clots during surgeries.

These drugs are not lifestyle medicines but true life-saving interventions. They remain indispensable for acute, life-threatening conditions.

The Problem with Pharmaceutical Dominance in Chronic Diseases

Let me point out, chronic lifestyle diseases (diabetes, heart disease, high blood pressure, etc.) cannot be  "cured" by drugs, they are simply managed indefinitely. This benefits Big Pharma, which profits from lifelong patients.

Examples of chronic disease drugs that do not "cure" are: 

Statins (e.g., Lipitor, Crestor) – Reduce cholesterol but don’t address the root cause of cardiovascular disease.

Unfortunately most of the diseases today are chronic illnesses that do not require fast-acting emergency drugs. 
 
It’s always a pleasure for me to engage in thought-provoking discussions with my medical colleagues, including highly qualified physicians, patients and lay readers on the current state of pharmaceutical medicine and compare them with other more natural systems of medicine that were already practised for over 5,000 years. 

Instead of using drugs let us dive into integrative medicine first.    

Integrative medicine is an approach that combines conventional allopathic (western) medicine with evidence-based complementary therapies to treat the whole person - body, mind, and spirit, rather than just the symptoms of disease. It focuses on lifestyle, nutrition, mind-body connection, and natural therapies alongside conventional treatments like pharmaceuticals and surgery.

I see several key strengths and considerations regarding integrative medicine:

Strengths of Integrative Medicine

1. Holistic Approach – It considers not just the disease but also the patient’s overall well-being, including diet, stress, sleep, exercise, and emotional health. This is in line with modern understanding that lifestyle factors significantly impact chronic diseases like diabetes, cardiovascular diseases, and even cancer.

2. Personalized Treatment -  Integrative medicine often tailors treatments to individual patients, considering genetic, environmental, and lifestyle factors. This agrees well with the emerging field of personalized medicine.

 3. Preventive Care Focus -  Unlike conventional medicine, which often focuses on treating diseases after they appear, integrative medicine strongly emphasizes prevention, which is key to reducing the burden of chronic diseases.

4. Less Dependence on Pharmaceuticals - While conventional medicine heavily relies on drugs, integrative medicine incorporates non-pharmaceutical treatments like acupuncture, herbal medicine, meditation, and nutritional therapy, which can sometimes be equally effective and have fewer side effects.

5. Scientific Basis for Some Complementary Therapies - Some integrative approaches, such as mindfulness, yoga, and plant-based nutrition, have strong scientific backing in improving health outcomes, especially in mental health, inflammation reduction, and chronic pain management.

Challenges and Considerations

1. Lack of Regulation and Standardization -  Unlike pharmaceuticals, many complementary therapies do not undergo rigorous clinical trials, making quality control and efficacy harder to verify. Some herbal remedies, for example, may have variable potency or interact with prescription drugs.

2. Risk of Pseudoscience - Some practitioners incorporate unproven or even harmful treatments. It is crucial to differentiate evidence-based integrative medicine from pseudoscientific or exaggerated health claims.

3. Mainstream Resistance - Despite growing interest, some conventional doctors view integrative medicine with skepticism, often due to the lack of extensive large-scale clinical trials for many complementary therapies.

4. Economic and Industry Influence - The pharmaceutical industry has long shaped modern medicine, sometimes limiting the integration of alternative approaches. This raises concerns about conflicts of interest and whether the best treatment options are always prioritized.

I see integrative medicine as a promising approach if it is grounded in scientific evidence. The future of medicine should not be a battle between conventional and alternative medicine but rather a fusion of the best, based on rigorous scientific validation. The ultimate goal should always be what benefits patients the most with the least harm.

The list of 50 integrative doctors I like to provide here as examples including well-known figures like Dr. Mark Hyman and Dr. Andrew Weil who show that even highly trained conventional physicians see the value in integrating nutrition, lifestyle, and natural therapies into medical practice. This is an encouraging trend.

Besides this list there are also other medical doctors and immunologists and scientists who too believe the body can heal itself if injured or diseased given the appropriate stimuli. 

Among the medical doctors are: 

1. Professor Dr Chang Jia Rui, MD a Taiwanese physician who wrote the book “The Body’s Natural Instinct: Understanding Your Body’s Healing Ability” . Professor Chang is the Honorary Professor and Chairman of the World Natural Medicine Foundation 

2.  Dr Vernon Coleman MD who wrote several books about the body as a natural medicine that can heal itself. Among the many books he wrote are: 1. Body Power 2. How To Stop Your Doctor Killing You 3. Anyone Who Tells You Vaccines Are Safe and Effective is Lying 4. Twelve essential medical secrets which could save your life 5. Mindpower: How to Use Your Mind to Heal Your Body. 

3.  Dr Jau-Fei Chen PhD who is a Nutritional Immunologist 

4. Dr Niwa MD, PhD (Med), a well-known Japanese physician, immunologist and researcher who wrote a book called “Drugs Do Not Cure Disease” 

Integrative medicine continues to gain recognition as healthcare professionals worldwide acknowledge the body's inherent ability to heal when provided with appropriate support. Beyond the practitioners I  mentioned, numerous other doctors and scientists advocate for combining conventional medical treatments with complementary therapies to promote holistic healing. Here are some further notable figures in the field:

1. Dr. Andrew Weil, MD

Background: A pioneer in integrative medicine, Dr. Weil is the founder and director of the Andrew Weil Center for Integrative Medicine at the University of Arizona.

Contributions: He emphasizes the body's natural healing capacity and advocates for a balanced approach that includes nutrition, mind-body interventions, and botanical medicines.

2. Dr. Mark Hyman, MD

Background: A family physician and a leading advocate for functional medicine, Dr. Hyman is the Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine.

Contributions: He focuses on identifying and addressing the root causes of chronic diseases through personalized treatments, including dietary changes and lifestyle modifications.

3. Dr. Avni Sali, MD, PhD

Background: An Australian surgeon and academic, Dr. Sali is the founder of the National Institute of Integrative Medicine (NIIM) in Melbourne.

Contributions: He has been instrumental in promoting integrative medicine in Australia, emphasizing evidence-based complementary therapies alongside conventional treatments.

4. Dr. Deepak Chopra, MD

Background: An endocrinologist and a prominent figure in mind-body medicine, Dr. Chopra has authored numerous books on health and wellness.

Contributions: He integrates principles from Ayurveda with modern medicine, focusing on meditation, yoga, and the mind's role in health and healing.

5. Dr. Joseph Mercola, DO

Background: An osteopathic physician, Dr. Mercola advocates for natural health approaches and preventive care.

Contributions: He emphasizes the importance of nutrition, exercise, and natural therapies in maintaining health and preventing disease.

6. Dr. Tieraona Low Dog, MD

Background: A physician with extensive training in herbal medicine, midwifery, and massage therapy, Dr. Low Dog has served on the faculty of the University of Arizona Center for Integrative Medicine.

Contributions: She focuses on women's health, dietary supplements, and integrative approaches to health and wellness.

7. Dr. David Katz, MD, MPH

Background: A preventive medicine specialist and founder of the Yale-Griffin Prevention Research Center.

Contributions: Dr. Katz emphasizes the role of lifestyle and nutrition in preventing chronic diseases and advocates for integrative approaches to healthcare.

These practitioners, among others, have significantly contributed to the field of integrative medicine, promoting a holistic approach that combines the best of conventional and complementary therapies to support the body's natural healing processes.

There is also a very thick and voluminous book I have called: “Integrative Medicine” 

This book is edited by Dr David Rakel MD who is a Professor and Chair Dept. of Family and Community Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico. 

He edited this massive book written and contributed by over 100 specialist physicians, most of them with not just a medical MD degree, but also armed with additional qualifications such as,  MSc, MS, ND, MPH, MHS, DO, ABIHM, FACOFP, RD, ABOIM, FAAFP, FRCP, MTS. 

They all contributed chapters on conventional medicine together with other systems of medicine covering evidence-based references on medicine that incorporated botanicals, supplements, mind-body, lifestyle medicine, nutrition, exercise, spirituality, chelation therapy, disease-orientated approach among others.

I  think of doctors and other people these days are reverting to other therapeutic modalities especially integrative medicine rather than depending solely on pharmaceuticals that are actually chemicals derived from petrochemicals as what the link above "How modern medicine has been highjacked" clearly revealed. 

The book Integrative Medicine edited by Dr. David Rakel seems to be a monumental work in the field, reflecting the growing acceptance of integrative approaches by highly qualified medical professionals.

So Why Are More Doctors and Patients Turning to Integrative Medicine today? 

The shift towards integrative medicine and away from a sole reliance on pharmaceuticals is driven by several interrelated factors:

1. The Limitations of Pharmaceuticals

While pharmaceuticals have revolutionized medicine, their over-reliance has led to concerns about side effects, drug resistance, toxicity, and long-term dependency.

Many drugs treat symptoms rather than root causes, especially in chronic diseases like diabetes, hypertension, and autoimmune disorders.

Petrochemical origins of many drugs raise concerns about biocompatibility and environmental impact, leading some to explore plant-based or holistic alternatives.

2. The Rise of Chronic Diseases and the Failure of Conventional Models

The modern world is facing an epidemic of lifestyle-related diseases (obesity, metabolic syndrome, cardiovascular diseases, autoimmune disorders).

Pharmaceuticals manage these conditions but rarely cure them.

Integrative medicine addresses lifestyle factors - diet, stress, exercise, environmental toxins, rather than just medicating symptoms.

3. Scientific Validation of Traditional & Complementary Therapies

Research has increasingly validated many traditional and alternative treatments:

Botanicals: Curcumin (turmeric) for inflammation, berberine for diabetes, and resveratrol for cardiovascular health.

Mind-body medicine: Meditation, yoga, and tai chi are now scientifically recognized for reducing stress, inflammation, and even altering gene expression.

Gut microbiome: The link between the microbiome and immunity, mental health, and chronic disease has validated probiotic and nutritional interventions.

4. The Public’s Increasing Awareness and Demand

People are more informed these days on nutrition, natural medicine, and preventive health.

There is growing distrust in Big Pharma, partly due to the perception that the industry prioritizes profit over patient well-being.

Social media and global access to research have democratized medical knowledge, allowing individuals to explore alternatives.

5. Shift in Medical Education & Research

Major institutions (Harvard, Stanford, University of Arizona, Cleveland Clinic, etc.) now have integrative medicine departments.

The NIH and other global health bodies fund research into herbal medicine, nutrition, acupuncture, and mind-body therapies.

Even the World Health Organization (WHO) supports traditional medicine integration, recognizing its value in primary healthcare. According to WHO, 80 % or more of the world population including those from advanced countries and highly educated people uses traditional medicine after they became disgruntled with conventional allopathic medicine that did not cure them except to control the disease and symptoms

Patients get very dissatisfied and disappointed when asked just take all these petroleum chemicals called ‘medicines’ for life in their doctors'  beliefs these drugs could cure them of their diseases. 

The Ideal Future: A Balanced Approach

I believe that integrative medicine is the future of healthcare, but it should be:

 Science-based, incorporating only therapies that have proven efficacy.
 Personalized, considering genetics, environment, and lifestyle.
 Preventive, reducing the need for pharmaceuticals in the first place.

Pharmaceuticals still have a vital role in emergency medicine, infections, and critical care, but for chronic disease, a holistic and integrative approach is superior.

Do we think mainstream medicine will eventually shift towards this model, or will resistance from the pharmaceutical industry slow its adoption a prominent physician asked me?

If you were to ask my opinion, I think conventional allopathic medicine that uses petroleum products as ‘medicines’ to ‘cure’ has never ‘cured’ any disease especially lifestyle diseases like heart disease caused by high blood pressure and high cholesterol, stroke, asthma, coronary artery disease, and most types of cancers, etc, etc will not get very far as most patients are now very educated and very intelligent.   

The Big Pharma and the pharmaceutical industry purposely make it this way so that after spending billions of US dollars developing their drugs over 10 - 15 years, they need to continue to reap lifelong profits out of them. The patients themselves too, trust their doctors that their ‘medicines’ could permanently ‘cure’ them.

I think we can blame this on the history of drug industry. Let's have a look how all these problem began with a brief history of profit-driven drug manufacturing. 

For most of human history, medicines were derived from natural sources, plants, minerals, and animal products. Traditional systems like Chinese medicine, Ayurveda, and herbalism relied on these remedies. However, the industrial era and advances in chemistry led to a major shift toward synthetic drugs, transforming medicine into a highly profitable industry.

1. Early Natural Medicines

Before the 19th century, remedies were largely plant-based, such as willow bark (aspirin precursor) and cinchona bark (quinine for malaria). These were often prepared by herbalists, apothecaries, and traditional healers.

2. Rise of Synthetic Pharmaceuticals (19th – Early 20th Century)

  • 1804: Morphine was isolated from opium, marking the beginning of pharmaceutical chemistry.
  • 1856: William Henry Perkin’s accidental discovery of synthetic dyes inspired the chemical industry, which later contributed to drug synthesis.
  • 1897: Aspirin (acetylsalicylic acid) was synthesized by Bayer, one of the first blockbuster drugs, shifting medicine from natural extracts to lab-based production.

3. The Birth of Big Pharma (20th Century)

  • 1928: Alexander Fleming discovered penicillin, but it wasn’t until WWII that companies like Pfizer industrialized its production, showing the profit potential of mass-producing antibiotics.

  • 1950s – 1970s: The pharmaceutical industry exploded with drugs like corticosteroids, benzodiazepines, and statins. Synthetic drug patents allowed companies to monopolize medicines and generate enormous profits.

  • Thalidomide Scandal (1950s-60s): The rush for profit led to ethical failures, such as the thalidomide tragedy, where a sedative caused birth defects.

4. The Patent-Driven Era (Late 20th Century – Present)

1. The 1980s-90s saw the rise of biotech and designer drugs, with companies shifting focus to patenting molecules rather than relying on nature.

2. The 1990s-2000s introduced high-profit chronic disease drugs, like statins and insulin analogs, often priced far beyond production costs.

3. Pharmaceutical lobbying and marketing grew, with companies spending more on advertising than research.

Current Landscape: Profits Over People?

1. The COVID-19 pandemic highlighted the tension between profit-making and public health, as vaccine patents limited global access.

2. Generic drugs remain under threat from evergreening (tweaking formulas to extend patents).

3. Natural medicine is often sidelined or dismissed as "unscientific," despite centuries of proven efficacy.



Thursday, July 10, 2025

"Echoes from the Old Schoolyard: Tales of My Naughty Schooldays"

Let me this evening share with my gentle readers vivid recollection that is both heartfelt and humorous, that carries deep nostalgia wrapped in rich cultural and personal history. 

“Across the Streets of Failure to the Cosmos of Curiosity: A Memoir of My School Days”

A dear senior engineer friend Ir. CK Cheong recently shared with me a picture accompanied by a poignant message:

"No one has travelled the road of success without crossing the street of failure. God never promised us an easy journey. He only promised us a great destination."

He went on to confide:


"I had my first failure when I failed my LCE (Lower Certificate of Education) and had to be detained in the same classes with my younger sister. Can you imagine how stressful I was?"

To that, I replied with a slice of my own past.

I, too, once tasted failure, an uncommon flavour in the banquet of my life. In 1956, during Form 3 at Batu Pahat High School, I failed the Malay paper in the newly introduced Lower Certificate of Education (LCE) examination. That year marked a significant shift in Malaya’s education system, the Malay language was included as a compulsory subject, and the experiment was thrust upon us like a sudden eclipse.

None of us, neither the Chinese, Indian, nor Malay students, had studied Malay as a subject. Our academic world was built entirely upon English. We didn’t even speak our mother tongues among ourselves. We were an English-speaking microcosm, forged by colonial curriculum and camaraderie. So when the Malay paper landed on our desks, it might as well have been written in Sanskrit.

The examination hall on the upper floor grew restless. We smiled nervously at each other, dumbfounded. After a half-hour of incomprehensible questions, an invigilator, perhaps moved by our bewildered faces, called out, "Whosoever cannot answer, stand up." To a man, we rose like a choreographed protest and surrendered our blank scripts. It was a moment of quiet solidarity. I failed only that one subject. Every other paper I passed. That was the only subject - an academic failure I ever had, from primary school to my Ph.D.

Later, in Forms 4 and 5, I wrote many essays in English. But my English teacher was not impressed. If he couldn’t understand my essay, he would erupt like Vesuvius, cursing me and hurling my exercise book out of the classroom onto the veranda, sometimes if violent enough past the veranda into the school drain, a good thirty metres away. Then he’d roared:

"How in the world you came into this class!"

As punishment, I would be asked to write 500 lines:

"I must write an essay that my teacher can understand."

But oh, but if I were to write an essay he could grasp, say, about cycling with friends to Minyak Beku a seaside 10 km away to picnic, swim, and enjoy ten-cent packets of nasi lemak wrapped in banana leaves, he would smile, shake my hand, and proclaim my essay was a true masterpiece.

I would in return grip his hand shaking it to share a similar masterpiece handshake.

Looking back now, I would bring flowers to his grave and silently kneel to forgive him, as my Lord Jesus taught. Those were the innocent and colourful days of youth.

I also remember vividly I was in Form 1, and wasn't eligible to study science until Form 3. But my curiosity refused to wait. My sister, two years my senior was in Form 3  studied at Temenggong Ibrahim Girls School (TIGS), about two kilometers from our boys High School Batu Pahat (HSBP). TIGS then had no science teacher or a science lab. Through some arrangement between schools the girls from TIGS would come over to HSBP for science classes in the afternoon when the HSBP morning sessions were dismissed. After morning classes, my sister would come to our school in the afternoon for science lessons. 

Though uninvited and ineligible, I often returned to my school still in my school uniform at 2 p.m. to sit quietly on the veranda outside the lab or leading by the science lab door watching Mr. Charly, the senior science master teach science to my sister and her classmates. I wasn't allowed inside. Mr Charly must have noticed the lone boy who always was there daily, sitting on the veranda outside the lab or leaning against the lab wooden door with unwavering eyes. He must have felt I was always there to learn something. He must have taken pity on me, and  never shoo me away.

One afternoon, I watched with childlike awe as he demonstrated how heating potassium chlorate (KClO₃) with manganese dioxide (MnO₂) as a catalyst produced oxygen. The gas bubbled through a delivery glass tube attached to the test tube into an inverted water-filled jar on a water trough and when the jar was sealed with a glass cover under water and taken out from the water trough and a glowing wooden splint was introduced, it burst into flame proving the jar was filled with pure oxygen.  I still remember the blinding brilliance when burning magnesium or sulphur was introduced into the jar of oxygen. I was spellbound. That invisible element, oxygen - had just unveiled a secret of the universe. Perhaps it was that spark that first whispered to me, "You could be a scientist".

On another day, Mr. Charly taught the girls about acids, and told them there were three kinds - concentrated nitric acids, concentrated sulphuric, and concentrated hydrochloric acid, and when water is added into each of them they became dilute nitric, dilute sulphuric, and dilute hydrochloric acids, and they were kept in separate bottles and labelled separately. 

Later at home, I challenged my sister asking her.

“How many kinds of acids they are?
“Three,” she said confidently. I told her she was wrong. There are six I told her. She stared at me with a confused frowned face quite a while. She asked me name the six. I rattled them off: concentrated nitric, concentrated sulphuric and concentrated hydrochloric acids,  and dilute nitric, dilute sulphuric and dilute hydrochloric acids - all six of them.
She was stunned and became even more puzzled. Then she retorted 

“But they’re the same acids, just in  diluted forms,” she countered.

 I then replied if they are  the same, then why label them separately and had to be kept separately in different bottles. So there must be six different kinds I challenged her.

She stared at me very confused, and after a short while called me a cheat. She refused to speak to me for a week after that.

Later, as a university chemistry student, I discovered the reality: there are over 80 known inorganic acids, from perchloric to chromosulphuric to hydrofluoric, and countless organic acids defined by the humble -COOH group. Carbon, with its infinite bonding potential, builds molecules that the human mind can only begin to catalogue.

Those early moments of wit and mischief were not confined to science class. I remember my math teacher, a long-sighted, with gapped and goofy teeth. When he read at the math text book he has to hold it at a distance and when he laughed he would hide his goofy teeth with his textbook on general mathematics by CV Durell, the mathematics book we used in Malayan schools then.

When maths class was over, and he left,   I, ever the mimic, would imitate him, to the laughter of my classmates. But he was cunning. He would pretend to leave the classroom, only to return silently by the back of the classroom and spy from the small openings between the tall colonial doors and the walls. Catching me in the act, he would spring out, strike my back, and sentence me to write:

"I must not laugh and imitate my teacher", - 500 lines by morning.

Manual labor followed as part of Saturday detention class by cleaning classrooms, scrubbing the school  latrines, dragging heavy steel rollers along with my other similar mischievous  "school criminals" across the school field to flatten the grass like ancient slaves building pyramids. I was a regular "school criminal" always sent to detention class - twice or three times a month. If not pulling rollers, I’d be made to stand on a chair at the back of the class, arms across my chest, tugging my ears in penance.

Yet, despite all this failures, punishments, detentions, and mischievous antics, these memories shine like stardust in my heart. They remind me that a child’s wonder, curiosity, and humour are not blemishes to erase, but constellations that illuminate the journey of learning.

I’m not only smiling at myself - at my own delightful school tales, but truly cherishing them. The innocence, mischief, and wonder of my youth shine like sunlight on morning dew, pure, nostalgic, and filled with life's poetry. What a privilege to walk with my readers and friends through these timeless corridors of memory.


Wednesday, July 9, 2025

My Personal and Global Journey through the Evolution of Computing


From Chalk and Log Tables to Supercomputers: A Personal and Global Journey through the Evolution of Computing

A Personal Prelude: When Arithmetic Was Manual and the Brain Was the Only Processor

I still remember vividly the early days of my primary school education in Batu Pahat High School - a small town where I was born and brought up in Johor, Malaya then, now called Malaysia.

 Long before anyone had heard of artificial intelligence or supercomputers, we relied solely on our memory and manual skills to perform even the simplest arithmetic. We were first taught addition and subtraction, then graduated to multiplication and division, all performed on paper or mentally. The multiplication table up to 12 times was a sacred tool, always printed on the back cover of our school exercise books, a humble yet powerful guide that we often memorised by heart.

As I progressed into lower forms in secondary school, mathematics became richer and more abstract: algebra, geometry, and trigonometry entered the curriculum. We began using logarithmic tables, printed in little blue books, to simplify multiplication and division of large numbers, an early form of computational aid. These tables were our analog calculators, and we took pride in being able to manipulate them with skill and understanding.

In Form 5 still in Batu Pahat High School and then in Singapore where I did my GCE A Levels in Science, we met calculus, a discipline that demanded a deeper understanding of limits, rates of change, and areas under curves. Every equation, every integral, and every derivative was solved painstakingly by hand. There were no shortcuts, only sheer intellectual effort and perseverance.

The Slide Rule Era: Precision by Hand

During my postgraduate studies at the University of London and later the University of Reading, I relied heavily on the slide rule, a fascinating analog instrument that allowed for multiplication, division, roots, logarithms, and even trigonometric functions. To us, it was an engineer’s or scientist’s portable computer. No batteries, no buttons, just a calibrated ruler and the sharpness of the human mind. The slide rule was a marvel of its time, a symbol of logic, mathematics, and manual precision.

The Dawn of Mechanical Calculators and Room-Sized Computers

By the late 1960s, when I began working professionally, I encountered the mechanical calculating machine, a heavy, clunky device with levers, gears, and rotating drums. We would crank or punch keys to perform basic arithmetic, and it was seen as a huge time-saver compared to manual calculations.

At about the same time, the first computers arrived at workplaces and universities. But they were not the sleek machines we know today. These were massive mainframe computers, often occupying an entire room, which had to be kept cold with four or more industrial air conditioners to prevent overheating, else it wont work. I remember we only have one computer stored in the Computer Room and for us to use the computer in turn.  We have to book for  'computer time'  in advance. The room was so cold that we literally had to wear winter clothings inside working in the computer room for hours. Their computing power was minuscule by today’s standards, yet they were revolutionary.

Using them was not straightforward. We had to learn computer languages such as BASIC, FORTRAN, and COBOL that were totally new to me. I had to attend courses for this, run by the Institute for Medical Research where I was working. Programming required punch cards and batch processing, nothing was instantaneous. I submitted my program and waited hours, sometimes days, for results. But for all their limitations, these early computers signaled a shift in how we processed information. They were the forerunners of everything that was to come.

Pocket Revolution: The Rise of the Electronic Calculator

Soon, the world witnessed the birth of the electronic pocket calculator, a compact device that could instantly compute addition, subtraction, multiplication, and division. Initially expensive and rare, they soon became ubiquitous. Later versions could handle trigonometric functions, logarithms, complex algebra, and even calculus. Some advanced models allowed for simple programming, making them portable computational powerhouses for students, engineers, and scientists alike. I remember when the first electronic calculator was available in the market, I would buy several of them, changing each version as they became more and more advanced within short periods with scientific features in them, later many of them were able to do complex mathematical calculations including calculus, and statistical calculations. As new versions became available that can be programmed, I would buy them to replace the older ones. I would buy a few of them for mathematical calculations for astronomy or physics as a hobby, or I would use them to analyze research statistical data gathered professionally for my medical research 

This was a silent revolution. With a calculator in our pocket, many of us felt we held in our hands the equivalent of what once required entire rooms.

The Microcomputer Revolution: Personal Computers in Every Home

The 1980s and 1990s saw the arrival of personal computers (PCs). Thanks to visionaries like Steve Jobs and Bill Gates, computers became increasingly affordable and accessible. No longer the domain of large institutions, ordinary people could now own and operate a computer from their homes. These machines used user-friendly operating systems like MS-DOS and later Windows and Mac OS.

Software flourished. Word processors, spreadsheets, and early internet browsers transformed how we worked, communicated, and learned. Graphical interfaces replaced command-line programming, and the world entered the digital age.

The Rise of the Internet and Cloud Computing

The late 1990s and early 2000s brought about the internet revolution. Computers were no longer isolated machines but part of a vast global network. Information, once locked in libraries or behind closed doors, became available to anyone with a connection. Email, websites, social media, and cloud storage redefined how we interact with knowledge and one another.

Cloud computing further removed the need for physical hardware. You could now access software, processing power, and storage over the internet. Computation became decentralized and borderless.

Harnessing the Titans of Thought: Applications of Supercomputers in Modern Science and Society

Parallel to these public revolutions, another quieter but more powerful transformation unfolded, the rise of the supercomputer. These colossal machines, with thousands or even millions of processing cores, are designed to solve the most complex, data-intensive, and iterative problems across the sciences and industry.

In the realm of quantum mechanics, supercomputers are essential for solving the time-independent Schrodinger equation in multi-particle systems. Using iterative numerical methods such as density functional theory or variational techniques, these calculations simulate electronic structures and energy states with high accuracy. This enables breakthroughs in materials science, quantum chemistry, and nanotechnology.

Modern supercomputers, like Fugaku (Japan), Frontier (USA), and LUMI (Europe), operate at speeds measured in exaflops, a quintillion (10^18) operations per second. To compare, a basic calculator might perform a few thousand operations per second.

Supercomputers vs. Ordinary Computers

FeatureOrdinary ComputerSupercomputer

Processing SpeedGHz-level (billions of operations/sec)Exaflop-level (quintillions/sec)
Number of Cores4 to 32Hundreds of thousands to millions
UsageEveryday tasks (email, documents)Complex simulations, AI training, climate models
StorageGB to TBPetabytes
AccessibilityPersonal, business, educationResearch labs, government, elite institutions
CostHundreds to thousands (USD)Hundreds of millions (USD)

In astrophysics, supercomputers are used to simulate nuclear fusion reactions at the heart of the Sun. The proton-proton chain, where hydrogen nuclei fuse into helium, involves quantum tunneling, plasma physics, and weak nuclear interactions, processes that demand enormous computing power to model precisely. These simulations help scientists understand stellar lifecycles, solar dynamics, and neutrino production. These calculations requires mathematical iterations that requires superspeed as the data changes 

Supercomputers also power climate modeling, integrating atmospheric, oceanic, and terrestrial data into massive, long-term simulations. These models project global warming trends, sea-level rise, and extreme weather events, and guide climate policy and environmental strategies.

In medicine and molecular biology, supercomputers simulate protein folding, drug-receptor binding, and enzyme kinetics using molecular dynamics and hybrid QM/MM models. This accelerates drug discovery, enabling virtual screening of compounds and optimizing them before clinical trials, saving both time and lives.

The rise of artificial intelligence has further amplified the role of supercomputers. Training deep learning models, such as those used in language processing, computer vision, and autonomous driving, involves billions of parameters and massive datasets. Supercomputers enable the iterative optimization processes that underlie machine learning and AI development.

In high-energy physics, supercomputers analyze experimental data from particle colliders, model quark-gluon plasmas, and simulate conditions just moments after the Big Bang. They help physicists decode the behavior of subatomic particles, contributing to the discovery of entities like the Higgs boson.

Engineers use supercomputers to run computational fluid dynamics (CFD) simulations for designing aircraft, rockets, vehicles, and buildings. These simulations predict airflow, turbulence, and structural stress, enhancing safety, efficiency, and innovation in design.

In cybersecurity and cryptography, supercomputers are employed to simulate encryption algorithms, detect vulnerabilities, and analyze massive network data for potential intrusions. They are also being used to explore quantum algorithms that could one day revolutionize digital security.

Economists and governments utilize supercomputers for macroeconomic forecasting, market simulations, and risk modeling. These systems simulate the behavior of entire economies using agent-based models, factoring in consumer behavior, trade flows, and geopolitical variables.

In genomics, supercomputers have revolutionized DNA sequencing, allowing scientists to process massive genetic datasets for understanding disease susceptibility, population migration, and personalized medicine. Epidemiologists also rely on supercomputers to simulate pandemic spread, guiding public health responses in real-time.

In every domain, from atoms to galaxies, from the genetic code to the economy, supercomputers allow us to ask and answer questions that were once far beyond our reach.

A Reflection Across Time

As I look back on my journey, from memorising multiplication tables and solving calculus problems by hand to now witnessing the dawn of AI and supercomputers, I am filled with awe. Not just at the machines themselves, but at the human mind behind them. Every generation built upon the last, combining logic, creativity, and perseverance.

From mechanical clanks to quantum entanglement, from punch cards to predictive AI, we have come a long way. And yet, we are only at the beginning.

Today, I am retired from all medical research and has gone into astronomy as my childhood marvels looking at the twinkling worlds up there in a dark opened skies 

More to Come

 Thank you to all for your letters and your patience. I can see in the statistics column several hundreds readers each day looking for my articles, old or new.  I shall continue to write and put new ideas here within 2 or 3 days each. It take a lot of time for me to search the literatures, then analyze them and think critically before I could write. 

In medical research as I did,  it took me years to churn up a paper. But here in my blog  it  is  much easier. Still I need at least a few days to search the literatures, how to simplify them for my ordinary gentle  readers 

Presently I have already written out 15 articles but  I can only release them just two per week, else I will be short of ideas 

Monday, July 7, 2025

Articles yet to be posted here

 Article yet to come in this blog


Non-Drug Management of Migraine

 

My sister-in-law Mary Chong Lee Moy who is recently a just retired Senior Nurse Clinician at the National University Hospital in Singapore phoned me this afternoon  from Johor Bahru complaining about her migraine. 

Let me take this opportunity to share my advice to her with other migraine sufferers too, especially for women reaching their menopause. 

Professor Dr SC Ling in a WhatsApp group also encouraged me to post this advice here so that others too can benefit  


Below is what I spoke to my sister-in law orally over the phone  

-----------------------------

 

Migraine Management & Relief 


Dear Mary,

Thank you for reaching out to me regarding your migraine concerns. I'm grateful for the opportunity to offer some support. Migraines can be complex and vary from person to person, but there are both immediate and long-term strategies that may help you manage them effectively.

Immediate Relief with Cold Compress Therapy

Applying cold compresses to both sides of the neck, forehead, and back of the head can be helpful in managing migraine pain. Cold therapy offers multiple benefits:

Vasoconstriction: Cold compresses narrow the blood vessels (especially the superficial carotid arteries), which may help counteract the vasodilation involved in migraines.

Numbing effect: Cold reduces nerve conduction and dulls pain perception.

Inflammation control: Cold limits the release of inflammatory mediators.

Muscle relaxation: It helps release neck and shoulder tension, a common migraine trigger.  

How to Apply:

Use a cold pack or crushed ice wrapped in a towel.
Apply for 15–20 minutes at a time, up to 4–6 times daily as needed.
Avoid direct ice contact to prevent skin burns.

Complementary Non-Drug Therapies

In addition to cold therapy, consider:

Meditation and mindfulness breathing (especially diaphragmatic breathing)

Progressive muscle relaxation (PMR)

Yoga for migraine (specific poses help relieve cervical tension)

Hypnotherapy: Clinical hypnosis can reduce stress-induced migraines. Some trials have shown reduced frequency and severity with consistent sessions

Acupuncture: Evidence supports its role in chronic migraine prevention

Avoiding Common Migraine Triggers

Lifestyle and environmental triggers are significant in migraine management. These include:

Environmental Triggers:

Bright or flickering lights (including sunlight through tree leaves).

Strong odors (smoke, perfume)

Noisy environments

Skipping meals or irregular sleep schedules.

Dietary Triggers (to avoid)

Aged cheese (tyramine content)

Red wine and other alcohol

Chocolate (phenylethylamine)

Processed meats (nitrates/nitrites)

Caffeine: For some, it relieves migraines; for others, it triggers or worsens them, especially with sudden withdrawal.

MSG, aspartame, citrus fruits, dried fruits, nuts, bananas, onions, avocados, garlic, and fermented/pickled foods.

It’s helpful to keep a migraine diary to track and identify individual food and lifestyle triggers.

 

Herbal and Natural Supplements:

Several herbs may help reduce the frequency or severity of migraines. However, dosage, purity, and drug interactions must be considered.

Feverfew (Tanacetum parthenium):

Mechanism: Reduces inflammatory prostaglandins, serotonin release, and platelet aggregation.

Dose: 100–300 mg daily of standardized extract (with 0.2–0.4% parthenolide).

Avoid during pregnancy.

Butterbur (Petasites hybridus):

Mechanism: Anti-inflammatory, antispasmodic on vascular walls.

Dose: 75 mg twice daily of PA-free (pyrrolizidine alkaloid-free) extract.

Not recommended for long-term use due to possible liver toxicity.

Ginger:

Useful for nausea and vomiting during migraine attacks.

Can be taken as tea, capsules (250 mg), or raw ginger.

 Melatonin:

Mechanism: Regulates circadian rhythm; modulates serotonin.

Dose: 3 mg at bedtime.

Especially useful in migraines with sleep disturbances or hormonal links.

White Willow Bark:

Contains salicin (like aspirin).

Dose: 120–240 mg salicin/day.

May be beneficial for general headache and pain relief.

Aromatherapy & Oils

Lavender oil: Inhalation or massage (2–3 drops diluted in carrier oil) may relieve migraines.

Peppermint oil: Apply diluted oil on temples or forehead for tension headache relief.

Conventional Migraine Medications

If migraines become more frequent or disabling, the following may be considered under a physician’s supervision:

Acute Migraine Relief:

Paracetamol (Acetaminophen): 500–1000 mg at onset.

NSAIDs: Ibuprofen 400–800 mg or Naproxen 500 mg.

Triptans (for moderate to severe attacks):

Preventive Therapy (if >4 attacks/month):

Beta-blockers: Propranolol 40–120 mg/day.

Calcium channel blockers: Verapamil.

Tricyclic antidepressants: Amitriptyline 10–75 mg/day.

Anticonvulsants: Topiramate (25–100 mg/day), Valproate.

These should be prescribed after full assessment.

 Caution with Herb–Drug Interactions

Feverfew may interact with NSAIDs or warfarin (increased bleeding)
.
Butterbur and melatonin may interact with liver-metabolized drugs

Herbs may affect the action of triptans, beta-blockers, antidepressants, and anti-seizure medications.

Always consult a healthcare provider before starting herbal supplements, especially when taking conventional medication.

Please let me know how you feel after trying the cold compress therapy alone. If it helps even partially, it’s a good sign. Then you may proceed to trial feverfew and melatonin or butterbur, depending on your tolerance and medical history.

You are not alone in this. Migraine is a complicated but manageable condition. Let us work together to explore the best strategy that suits your unique case.

 As a care-giver, I am one who sees beyond pills into the person.

Take care always, dear Mary. I’m here anytime you need me.

With blessings, and  brotherly love

lim ju boo 


(Articles yet to come in this blog): 


Allopathic Medicine and Traditional & other Complementary Medicine

by: lim ju boo Professor Dr Marilyn Li Ching who is a regular contributor in a WhatsApp group recently sent me this video for my comment.  1...